This work analyzed the profitability of Neem seed marketing in Yobe State, Nigeria. Purposive sampling technique was used in selecting Afunori, Nangere and Damaturu Neem plantations established in 1999.The study involved 25 marketing respondents selected based on Yero Yemeni’s model. Primary data were collected using structured questionnaires and the variables on which data were collected included socioeconomic characteristics, marketing costs and revenues and same were analyzed using descriptive statistics, multiple regressions, gross margin and profitability analyses. Socioeconomic results revealed that the marketing scenario was dominated by none-literate, male, married youth farmers whose mean age and marketing experiences were 36.88 and 8.74 years respectively. Respective unit increase in marketing experience and educational levels significantly raised profits by only N8.76 and N2.14, whereas same unit increase in purchase and operating costs recorded significant profit reduction by N4,792.92 and N8, 508.36 respectively. Of the total of 673.13 tons of neem seeds marketed between 2009 and 2013, only ₦1, 136.25 GM/ton/marketer was realized. Similarly, net profit per ton per marketer stood at only ₦949.12 within the same period. The study concluded that neem seed marketing wasn’t profitable in the study area. Creation of markets and Neem associations was the major policy recommendation made.

Key words: Analysis, Profitability, Neem Seeds